mfsig.com
mfsig.com · 3D viewer

Open a .mfsig.json, see the molecule

samples
assembled · dimer· B3LYP/def2-SVP + D3BJ · BSSE-corrected · ΔE in kcal/mol
ASD · drug × polymer· Flory-Huggins χ at 298 K · ΔE in kcal/mol
no data loaded

σ-profile · 51-bin histogram

e / Ų

σ-charge density on the COSMO cavity, weighted by tile area. Left lobe = donor surface (H-bond donors), right lobe = acceptor surface (H-bond acceptors), centre lobe = apolar. Integrates to the total cavity area (Ų).

Download · convert

Conversion is client-side and lossy by design. The .mfsig.json is the canonical signed file — everything else is a derived format for external tools.

Reading the canvas

  • donor · −σ tile · H-bond donor surface
  • apolar · |σ| < HB cutoff (0.0084 e/Ų)
  • acceptor · +σ tile · H-bond acceptor surface
Confidence legend
HIGH · gate-checked MED · known systematic limit LOW · research only
→ every .mfsig field, typed and graded

Audit pack · the engine

21 CFR Part 11 · ALCOA-compatible · tamper-evident
.mfsig 2.0-apex
SHA-256 checksum
UUID
timestamp · UTC
engine
Method · what produced this file
DFT
functional
basis set
D3BJ
dispersion
Bondi
cavity radii
water
solvent
NaN
dielectric ε
vdW
cavity model
relaxed‖∇E‖<1e-3
geometry